What are the side effects from Paxlovid? One of them is Swelling of the Mouth, Lips or Face

Healthy - The most common side effects of taking Paxlovid include impaired sense of taste (for example, a metallic taste in the mouth) and diarrhea, according to the FDA. 

Most people who take Paxlovid should not experience serious side effects, explains Dr. Roberts. “Paxlovid is usually very well-tolerated,” he says.

But people should stop taking Paxlovid and call a health care provider right away if they experience any of the following signs of an allergic reaction:

- hives

- trouble swallowing or breathing

- swelling of the mouth, lips, or face

- throat tightness

- hoarseness

- skin rash

Other possible side effects include:

- an altered or impaired sense of taste

- diarrhea

- increased blood pressure

- muscle aches

- abdominal pain

- nausea

- feeling generally unwell

Since Paxlovid is cleared by the kidneys, dose adjustments may be required for patients with mild-to-moderate kidney disease, explains Dr. Topal. 

“For patients with severe kidney disease—or who are on dialysis—or those with severe liver disease, Paxlovid is not recommended; the levels of the drug can become too high and could cause increased side effects,” he says.

The FDA says that anyone who takes Paxlovid should contact their health provider right away if they have any signs and symptoms of liver problems: loss of appetite, yellowing of the skin and whites of the eyes (jaundice), dark-colored urine, pale-colored stools and itchy skin, or stomach-area (abdominal) pain.

It’s worth noting that because Paxlovid is still being monitored in the real world, it is possible that all of the risks are not yet known. (The FDA has provided a fact sheet on Paxlovid with a full list of known side effects.)***

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